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Syracuse, votre nouveau portail documentaire !
Nous avons le plaisir de vous annoncer le lancement du tout nouveau portail documentaire interne de l'Anses ! Cet outil, que nous avons voulu intuitif et accessible à tous, rassemble en un seul endroit toutes les informations utiles à votre quotidien pour vous faire gagner du temps : catalogue des ressources, informations sur la science ouverte, bonnes pratiques de publication, FAQ sur l'IA...
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Article
Comparison of sensitivity to methyl-methanesulphonate among tadpole developmental stages using the alkaline single cell gel electrophoresis (comet) assay
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Integration of in vitro approaches to predict drug metabolism and interaction in man: an eu validation project
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Suspicion de syndrome de Stevens-Johnson chez un cheval après administration de sulfamides : quel est votre avis ?
Le 1 er août, suite à la découverte d'une fistule mandibulaire, une antibiothérapie basée sur une association de sulfaméthoxypyridazine et de triméthoprime est prescrite à un cheval selle français de 18 ans.
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Epidemiological rabies surveillance for the Americas. February 1977 2. Rodent rabies - United States of America
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Spatial and temporal distribution of rabies in northern Tanzania in the period of 1993-2002
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Validated method for the therapeutic drug monitoring flunitrazepam in human serum using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry with an ion trap detector
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Histochemical localization of cell proliferation using in situ hybridization for histone mRNA
Monoclonal antibodies to proliferation associated antigens have long been used to histologically localize mitogenesis. However, techniques that distinguish cells in the synthetic or S phase have tended to rely on the in vivo incorporation of tritiated thymidine or thymidine analogs such as bromodeoxyuridine. The necessity to pulse with these labels before retrieving tissue means that they cannot be used in humans and are not available retrospectively. Measuring expression of histones serves as a useful adjunct to these techniques. As expression of histone proteins (H2A, H2B, H3, H4) are restricted to the synthetic phase of the cell cycle, hybridization for histone mRNA precisely distinguishes those cells in the S phase. Measuring their expression can easily be applied to the histological localization of proliferation, and can be used both prospectively and with archived tissue specimens. Several histone in situ hybridization probes and nonradioactive detection systems are now available commercially. A generalized protocol for their use in measuring in situ proliferation is provided in this chapter.